Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the cure of various myeloma. Its synthesis or study is crucial for making sure the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the procedure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise forms of cancer, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is significant Androsta-5 for optimizing the manufacturing course of action and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the therapy of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride 16-dien-3beta-ol 3-acetate Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have various programs, which include antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for variety two diabetes that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of varied gluconic acid derivatives, which are used in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication made use of to control form 2 diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).